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Ketamine Therapy Clinics in Colorado

Browse 71 medical ketamine centers and 196 ketamine-assisted psychotherapy providers in Colorado. Find IV infusion, Spravato, telehealth, and KAP providers for depression, anxiety, PTSD, and more.

Providers
267
Cities
51
Medical centers
71
KAP therapists
196

Ketamine Therapy in Colorado

Provider landscape across Colorado

Colorado hosts one of the country's most robust ketamine treatment ecosystems. Ketamine Atlas lists 267 providers across the state — 71 medical clinics and 196 ketamine-assisted psychotherapy (KAP) practices — spanning 51 distinct cities from the Front Range into the mountains. That breadth means patients across most of Colorado can find some form of local access without extensive travel. The sheer variety of provider settings, from hospital-affiliated psychiatric programs to independent KAP therapists, reflects just how broadly ketamine care has taken hold here.

Treatment modalities available

The range of delivery methods in Colorado mirrors the field's broader evolution. Ketamine-assisted psychotherapy is the most common approach, with 196 providers offering it; KAP combines a ketamine experience with structured therapy sessions guided by a licensed mental health professional, and is frequently used for depression, anxiety, PTSD, and trauma. IV infusion is offered by 108 providers — administered intravenously in a supervised clinical setting, typically across a series of sessions. Spravato (esketamine), the FDA-approved nasal spray for treatment-resistant depression, is available through 62 providers; unlike IV ketamine, Spravato carries FDA approval and may be eligible for insurance coverage through many plans. Intramuscular (IM) injection is offered by 6 providers, and a small number of listings include telehealth-connected options.

Browse by City (51)

Each city page lists every local provider with treatment details.

Cities with the most providers

All 51 cities in Colorado, A–Z

All Providers in Colorado (267)

Medical Centers (71) Clinics offering IV infusion, IM injection, Spravato (esketamine nasal spray), and other medical ketamine treatments.

Ketamine-Assisted Psychotherapy (196) Licensed therapists offering ketamine-assisted psychotherapy (KAP) for depression, anxiety, PTSD, and trauma. Often paired with at-home protocols.

Showing 24 of 267 providers in Colorado

Ketamine therapy across the Front Range and beyond

Denver leads the state with 70 listed providers — about a quarter of all Colorado listings — making it one of the densest ketamine markets in the country. Boulder follows with 34, reflecting that city's deep investment in mental health and wellness services. Colorado Springs has 23 listings and Fort Collins 19. Lakewood contributes 12; Arvada, Aurora, and Longmont each have 7; Wheat Ridge, Durango, and Littleton each have 6. Even Centennial has 4 provider listings. Patients in rural areas may find that a short drive to a Front Range city significantly expands their options.

Choosing a provider and understanding cost

Ketamine treatment in Colorado takes several forms, and the right fit depends on your clinical history, diagnosis, and personal goals. Medical approaches like IV infusion and Spravato are overseen by physicians or nurse practitioners; KAP places a licensed therapist at the center of the process. Some Colorado practices offer integrated models combining both. IV and IM ketamine are generally considered off-label uses for mental health and are typically out-of-pocket. Spravato, being FDA-approved for treatment-resistant depression, often has a distinct insurance pathway — check with your insurer and the provider. Use the listings on this directory to compare treatment types and provider backgrounds, and reach out directly to any clinic to confirm current availability, fees, and intake requirements.