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Ketamine Therapy Clinics in Pennsylvania

Browse 77 medical ketamine centers and 62 ketamine-assisted psychotherapy providers in Pennsylvania. Find IV infusion, Spravato, telehealth, and KAP providers for depression, anxiety, PTSD, and more.

Providers
139
Cities
70
Medical centers
77
KAP therapists
62

Ketamine Therapy in Pennsylvania

What Pennsylvania's directory reveals

Pennsylvania's 139 listed ketamine providers are spread across 70 distinct cities — a notably broad geographic reach that includes both major metros and smaller communities throughout the state. Of those listings, 77 are medical clinics and 62 offer ketamine-assisted psychotherapy, giving patients a real choice between clinical and therapy-centered models of care. The state's 70-city spread is one of the widest in the Northeast, reflecting consistent demand outside Philadelphia and Pittsburgh.

Available treatment types

Spravato (esketamine) is the most widely offered treatment in Pennsylvania, with 73 providers listing it. As the only FDA-approved form of ketamine specifically indicated for treatment-resistant depression, Spravato is administered in-office as a nasal spray under monitoring; many insurance plans have coverage pathways for qualifying patients. Ketamine-assisted psychotherapy (KAP) follows closely with 62 providers — this model integrates a licensed therapist into ketamine sessions to support therapeutic goals around depression, anxiety, PTSD, and trauma. IV infusion is available from 44 providers, representing an intravenously delivered, medically supervised format that remains one of the more established clinical approaches. A small number of Pennsylvania providers (4) also offer telehealth services, which may benefit patients in less populated parts of the state.

Browse by City (70)

Each city page lists every local provider with treatment details.

Browse by Metro Area:

Philadelphia

Cities with the most providers

All 70 cities in Pennsylvania, A–Z

All Providers in Pennsylvania (139)

Medical Centers (77) Clinics offering IV infusion, IM injection, Spravato (esketamine nasal spray), and other medical ketamine treatments.

Ketamine-Assisted Psychotherapy (62) Licensed therapists offering ketamine-assisted psychotherapy (KAP) for depression, anxiety, PTSD, and trauma. Often paired with at-home protocols.

Showing 24 of 139 providers in Pennsylvania

Where providers are concentrated

Philadelphia leads with 35 listings, followed by Pittsburgh at 20 — together accounting for nearly 40 percent of all Pennsylvania providers. Beyond those two cities, coverage is spread widely: Harrisburg, Bala Cynwyd, West Chester, and Doylestown each have 3 listings. Lancaster, Millvale, Allentown, Altoona, Villanova, and Newtown each have 2. The 70-city footprint means patients outside the major metros still have meaningful local access in many cases, particularly for Spravato.

Navigating costs and finding the right fit

IV infusion and off-label IM ketamine are typically out-of-pocket expenses not covered by standard insurance. Spravato is a distinct case — its FDA-approved status means insurance coverage may be available, though specific authorization requirements vary by plan and diagnosis. KAP fees are set by individual practices and can differ considerably based on session length and provider credentials. Before pursuing treatment, call ahead to understand the financial model and intake process at any clinic you're considering. Use this directory to review provider details across Pennsylvania, then contact them directly to verify current pricing, scheduling availability, and what a typical course of care looks like.