Ketamine Therapy Clinics in South Carolina

Browse 42 medical ketamine centers and 19 ketamine-assisted psychotherapy providers in South Carolina. Find IV infusion, Spravato, telehealth, and KAP providers for depression, anxiety, PTSD, and more.

Treatments offered:IV InfusionKetamine-Assisted PsychotherapySpravato (Esketamine)

Medical Centers (42)

Clinics offering IV infusion, IM injection, Spravato (esketamine nasal spray), and other medical ketamine treatments.

AVA MEYER

1301 Main St, Conway, SC 29526

Spravato (Esketamine)

843-703-1027

Barrier Islands Psychiatry

1616 ASHLEY RIVER RD, Charleston, SC 29407

Spravato (Esketamine)

843-556-8177

Bridges Psychiatry

115 Fairchild St, STE 170, Daniel Island, SC 29492

Spravato (Esketamine)

803-339-1563

Charleston Ketamine Center

1050 Johnnie Dodds Blvd Suite A, Mount Pleasant, SC 29464

IV Infusion

843-972-9934

Columbia Ketamine Center

1901 Gadsden St, Columbia, SC 29201

IV Infusion

803-973-4810

Continuum Health Providers

1188 Stonecrest Blvd STE 110, 1182 Stonecrest Blvd STE 102, Fort Mill, SC 29708

Spravato (Esketamine)

803-233-3236

Counseling for Life

1209 N Fant St, Anderson, SC 29621

Spravato (Esketamine)

864-353-3384

Daylight Wellness Group

251 Wall St, Piedmont, SC 29673

Spravato (Esketamine)

864-597-0159

Future Psych Ketamine Clinics

1601 N Oak St, STE 303, Myrtle Beach, SC 29577

Spravato (Esketamine)

843-788-9718

Future Psych Solutions

1911 GADSDEN STREET, SUITE 101, Columbia, SC 29201

Spravato (Esketamine)

803-851-0642

GONZALEZ, ALBERTO J MD

2323 ST MATTHEWS ROAD, Orangeburg, SC 29118

Spravato (Esketamine)

803-534-0042

Greenbrook Mental Wellness Centers

223 Adley Way, Greenville, SC 29607

Spravato (Esketamine)

866-921-4712

Greenbrook Mental Wellness Centers

3790 Fernandina Rd, STE 100, Columbia, SC 29210

Spravato (Esketamine)

866-921-4712

Greenville Ketamine Infusions

109 E Antrim Dr, Greenville, SC 29607

IV Infusion

864-920-5121

Inner Healing Charleston

1316 Rutledge Ave, Charleston, SC 29403

Spravato (Esketamine)

843-273-6532

Integrative Flow Psychiatry

214 University Pkwy, Aiken, SC 29801

Spravato (Esketamine)

803-716-8002

JENNIFER LYNCH

1268 S 4th St, Hartsville, SC 29550

Spravato (Esketamine)

843-332-3422

KAREN FULWOOD

A'Nucare LLC Wellness Center, 110 Cherry St, Darlington, SC 29532

Spravato (Esketamine)

843-992-2732

Ketamine Solutions, LLC

138 MILESTONE WAY, Suite A, Greenville, SC 29615

Spravato (Esketamine)

864-236-1630

Lifestance Health - Forest Acres

3600 Forest Dr, STE 302, Columbia, SC 29204

Spravato (Esketamine)

839-746-6262

Lowcountry Therapy

504 W 5th North St, Summerville, SC 29483

Spravato (Esketamine)

843-872-2954

MINDWELL

16 Mills Ave, STE 6, Greenville, SC 29605

Spravato (Esketamine)

846-735-8080

MINDWELL LLC

4126 Clemson Blvd, STE 2C, Anderson, SC 29621

Spravato (Esketamine)

864-735-8080

MUSC HEALTH CENTERSPACE

1470 Tobias Gadson Blvd ste 107, Charleston, SC 29407

Spravato (Esketamine)

843-876-1195

NATALI AMARADASA

401 79th Ave N, Myrtle Beach, SC 29572

Spravato (Esketamine)

910-504-3506

NGU AUNG

401 79Th Ave N, Myrtle Beach, SC 29572

Spravato (Esketamine)

910-504-3506

PALMETTO PAIN MANAGEMENT, LLC

2611 FOREST DR, STE 200, Columbia, SC 29204

Spravato (Esketamine)

803-779-3263

Radial

1086 London St, Myrtle Beach, SC 29577

Spravato (Esketamine)

843-703-1027

RICHARD BOWEN

570 Long Point Rd, STE 150, Mount Pleasant, SC 29464

Spravato (Esketamine)

843-480-2273

Summerville Behavioral Health

204 N CEDAR ST STE 100, Summerville, SC 29483

Spravato (Esketamine)

843-821-2480

Sweetgrass Psychiatry

710 JOHNNIE DODDS BLVD, STE 200, Mount Pleasant, SC 29464

Spravato (Esketamine)

843-800-1303

Sweetgrass Psychiatry

103 Palm Blvd, STE 2A, Isle Of Palms, SC 29451

Spravato (Esketamine)

843-800-1303

TANDI FORTIER

25 Woods Lake Rd, STE 321, Greenville, SC 29607

Spravato (Esketamine)

864-208-9501

Taral Sharma M.D., P.C.

60 Bear Dr, Greenville, SC 29605

Spravato (Esketamine)

864-844-9432

Taral Sharma MD PC

201 Central Park Ln, Seneca, SC 29678

Spravato (Esketamine)

864-844-9432

Taral Sharma MD PC

1071 Boiling Springs Rd, Spartanburg, SC 29303

Spravato (Esketamine)

864-844-9432

Taral Sharma MD PC

10 Financial Blvd, Anderson, SC 29621

Spravato (Esketamine)

864-844-9432

The Journey Behavioral & Wellness Clinic

926 Oakland Ave Ste 4, Rock Hill, SC 29730

Spravato (Esketamine)

803-693-6100

Turnwell Mental Health South Carolina PC

600 Seacoast Pkwy, STE 200, Mount Pleasant, SC 29464

Spravato (Esketamine)

843-868-2005

Western Carolina Psychiatric Associates

1033 Edgefield St, Greenwood, SC 29646

Spravato (Esketamine)

864-227-3908

WILLIAM HENDRICKS

201 CENTRAL PARK LN, Seneca, SC 29678

Spravato (Esketamine)

864-844-9432

ZARROUF, FAHD, A, (MD)

2000 E Greenville St Ste 1000, Anderson, SC 29621

Spravato (Esketamine)

864-512-4935

Ketamine-Assisted Psychotherapy (19)

Licensed therapists offering ketamine-assisted psychotherapy (KAP) for depression, anxiety, PTSD, and trauma. Often paired with at-home protocols.

Adina Silvestri

Charleston, SC

Hi, I’m Dr. Adina Silvestri, LPC. If you’re done with “just cope harder,” you’re in the right place. My work is soul-led and science-backed—integrating Internal Family Systems (IFS), clinical hypnosis, expressive writing, and (when appropriate) ketamine-assisted psychotherapy in collaboration with a

Ketamine-Assisted PsychotherapyIV Infusion
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Amber Hudson

Greenville, SC

There are moments in life when the ground beneath us feels shaky—when the ways we’ve always managed no longer seem to carry us through. What once worked suddenly doesn’t, and we can find ourselves feeling overwhelmed, lost, or even disconnected from the people and experiences that used to bring us j

Ketamine-Assisted Psychotherapy
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Angela Kearns

Charleston, SC

Are you feeling overwhelmed by the state of the world? If anxiety, uncertainty, or past experiences are weighing you down, you don’t have to navigate them alone. Whether you're facing personal challenges, healing from trauma, or struggling in relationships, I’m here to support you. My counseling st

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Chris Henrie Therapy, LLC

Greenville, SC

I use my knowledge of psychotherapy and life experiences to assist my clients in becoming the best they can be. I take an eclectic approach to mental health assisting my clients in finding the best in themselves and enhancing their creative abilities to better understand their emotions and behaviors

Ketamine-Assisted PsychotherapyIV Infusion
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Daniel Ripley

Mount Pleasant, SC

Ketamine-Assisted Psychotherapy
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Emily Williams

Greenville, SC

Trauma comes from a variety of different places and a variety of different experiences. People who have faced trauma may find it difficult to connect with themselves or focus on their hopes, dreams, and goals. I have been working with adolescents and adults facing difficult life challenges for over

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Gabby Lux

Greenville, SC

Imagine a version of yourself that is fully authentic, aligned, and free. A version of yourself that is no longer carrying the weight of depression, trauma, or anxiety; No longer fighting, pretending, or compartmentalizing to coexist with the impacts of your past. Right now, you might feel like clar

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Joshua Smith

Summerville, SC

Accepting new clients! I create a positive space where you can feel heard, understood, and valued for your experiences while also receiving constructive feedback. I have experience working with people that have depression, anxiety, trauma, gender dysphoria, identity issues, and self-esteem issues.

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Joslyn Hawver

Myrtle Beach, SC

Joslyn is passionate about providing compassionate, evidence-based care that supports the whole person. She works with adults facing a wide range of emotional and psychological concerns—including anxiety, depression, trauma, relationship challenges, and ADHD. She blends evidence-based interventions

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Lightwell Counseling

Mount Pleasant, SC

Our clients are adults and couples who feel stuck in patterns they don’t fully understand—whether in relationships, emotional reactions, or life direction. Many come in navigating anxiety, trauma, or disconnection, often after trying to push through on their own without lasting relief. They’re not j

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Lindsey Fox

Charleston, SC

You’re high-functioning but exhausted. You may live with ADHD, complex trauma, or chronic stress and feel stuck between knowing what you “should” do and not being able to follow through. You carry emotional awareness, responsibility, and self-doubt all at once. You want relief, clarity, and to final

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Meredith Little

Charleston, SC

You have been disconnected from yourself, others, your body for too long. Trying to find your way back home has felt impossible. Your needs and identity are a long-away dream and anger and resentment seem your constant companions. You used to dance in the kitchen and now stand with gritted teeth wa

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Pearson Psychological and Evaluation Services

Myrtle Beach, SC

Are you a Veteran seeking a Nexus letter/Independent Medical Opinion? My primary focus is on providing Mental Health Evaluations and Nexus letters for Veterans seeking mental health benefits from the VA. I have helped many veterans through the process, including preparing them for their C&P exam, ob

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Rachel Bilbo

Charleston, SC

Are you feeling overwhelmed or bombarded by negative thoughts? Stuck in old patterns and ways of reacting? Struggling with your spirituality? Or maybe you’re just feeling empty inside. Whatever it is, I am here to help. Together we will explore the internal and external obstacles which keep you feel

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Rachel Kelley

Aiken, SC

When life's journey has you feeling lost, overwhelmed, or uncertain, it can help to have someone to guide you through its new twists and turns. I act as a Therapeutic Cartographer, helping you map your way, equipping you with knowledge and tools, mindful of areas that might take you off your intend

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Resilient Roots Therapy - San Pao, Clinician

Mount Pleasant, SC

As a combat veteran, I know firsthand the weight of trauma, transitions and the unique challenges men face when carrying invisible wounds. My practice is dedicated to serving veterans, first responders, and others who have experienced trauma, as well as, men navigating identity, relationships, and r

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Tamara Stainton

Seneca, SC

I recognize that our clinical world hasn’t always treated everyone with the care, dignity, and understanding they deserve. Many diagnosis and demographics remain disenfranchised, overlooked, or misunderstood. This reality is exactly why I’ve chosen to narrow my practice to serve the listed populatio

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Upstate Integrative Mind Counseling

Greenville, SC

At Upstate Integrative Mind Counseling, we provide therapy that is compassionate, skilled, and tailored to the individual. We understand that emotional pain can show up in many forms: stress, trauma, relationship conflict, overwhelm, disconnection, or patterns that feel hard to we believe treatment

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Veronda Bellamy

Columbia, SC

Congratulations on taking such a huge step in reaching out for guidance - someone that can partner with you on your life's journey. It is critical that you secure a safe place to process your feelings. I get it, feeling stuck can grip you into paralysis. You feel overwhelmed, you feel disconnected,

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Ketamine Therapy in South Carolina

There are 61 ketamine clinics and providers across South Carolina, covering 20 communities. Of these, 42 are medical ketamine centers (offering treatments like Spravato (esketamine) and IV ketamine infusion) and 19 are licensed therapists offering ketamine-assisted psychotherapy (KAP).

The largest concentrations are in Greenville (11), Charleston (8), Mount Pleasant (7), Columbia (6), and Myrtle Beach (6).

Across South Carolina, the treatment options represented include Spravato (esketamine), ketamine-assisted psychotherapy, and IV ketamine infusion. Spravato (esketamine) is an FDA-approved nasal spray typically covered by insurance for treatment-resistant depression, while IV and IM ketamine are usually offered off-label for depression, anxiety, PTSD, and chronic pain.

Browse the full list of providers above, or narrow by city to find ketamine therapy near you. Every listing links directly to the provider so you can verify current availability, treatment types, and insurance before booking.