Ketamine Therapy Clinics in South Dakota

Browse 13 medical ketamine centers and 1 ketamine-assisted psychotherapy provider in South Dakota. Find IV infusion, Spravato, telehealth, and KAP providers for depression, anxiety, PTSD, and more.

Treatments offered:IV InfusionKetamine-Assisted PsychotherapySpravato (Esketamine)

Medical Centers (13)

Clinics offering IV infusion, IM injection, Spravato (esketamine nasal spray), and other medical ketamine treatments.

Ketamine-Assisted Psychotherapy (1)

Licensed therapists offering ketamine-assisted psychotherapy (KAP) for depression, anxiety, PTSD, and trauma. Often paired with at-home protocols.

Brooke Leonard Psychotherapy

Sioux Falls, SD

Improving your relationship with yourself and others is important work. I want to partner with you to move from suffering to thriving. With effective treatment, permanent healing of emotional wounds is possible. That's a big statement, but advancements in psychological health have made huge strides.

Ketamine-Assisted PsychotherapyIV Infusion
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Ketamine Therapy in South Dakota

South Dakota has 14 ketamine therapy providers listed on Ketamine Atlas, spread across 5 cities. Of these, 13 are medical ketamine centers (offering treatments like Spravato (esketamine) and IV ketamine infusion) and 1 is a licensed therapist offering ketamine-assisted psychotherapy.

The largest concentrations are in Sioux Falls (7), Rapid City (4), Pierre (1), Aberdeen (1), and Watertown (1).

Across South Dakota, the treatment options represented include Spravato (esketamine), ketamine-assisted psychotherapy, and IV ketamine infusion. Spravato (esketamine) is an FDA-approved nasal spray typically covered by insurance for treatment-resistant depression, while IV and IM ketamine are usually offered off-label for depression, anxiety, PTSD, and chronic pain.

Browse the full list of providers above, or narrow by city to find ketamine therapy near you. Every listing links directly to the provider so you can verify current availability, treatment types, and insurance before booking.